Sodium Carbonate → 1,3-Bis[4-(2-formylhydrazino)phenyl]thiourea

HRID 437505

Reaktionsgleichung

Reaktionsgleichung von HRID 437505
[C:1](=[O:4])([O-])[O-].[Na+].[Na+].C(CS[C:12](=[S:18])SCC(O)=O)(O)=O.[CH:19]([NH:21][NH:22][C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=1)=[O:20]>O>[CH:19]([NH:21][NH:22][C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:12]([NH:29][C:26]2[CH:27]=[CH:28][C:23]([NH:22][NH:21][CH:1]=[O:4])=[CH:24][CH:25]=2)=[S:18])=[CH:25][CH:24]=1)=[O:20]

Komponenten

5

Edukt 3

HCID 10340Sodium Carbonate2×HCID 806183,5-Dithia-4-thioxo-1,7-heptanedioic acidHCID 113189Hydrazinecarboxaldehyde, 2-(4-aminophenyl)-

Produkt 1

HCID 196096521,3-Bis[4-(2-formylhydrazino)phenyl]thiourea

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
95 °C

Versuchsvorschrift

Sodium carbonate (2.1 g, 0.02 mole) was dissolved in water (100 ml). Bis(carboxymethyl)trithiocarbonate (4.5 g, 0.02 mole) was added portionwise with vigorous stirring. The pH of the reaction mixture was adjusted to 9.5 by the addition of sodium carbonate. The mixture was then heated to approximately 95° C. 1-Formyl-2-(4-aminophenyl)hydrazine (6.5 g, 0.043 mole) was added in one portion to the reaction mixture. Stirring was continued for five minutes. The reaction mixture was chilled, the solid was filtered off, washed thoroughly with water and dried. Yield 4.5 g (66%), m.p. 212°-214° C.

Aufarbeitung

  1. temperatureThe reaction mixture was chilled
  2. filtrationthe solid was filtered off
  3. washwashed thoroughly with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-f4c763f4313b47ef8803fcb9d19cbe4f
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04031127

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