2-Ethylhexyl acrylate → Ethylhexyl 2,4,5-trifluorocinnamate

Beteiligte Stoffe

Reaktionsschritte

3.0 g (14.2 mmol) of 1-bromo-2,4,5-trifluorobenzene are refluxed under protecting gas with 30.0 mmol of 2-ethylhexyl acrylate, 140 mg of palladium on activated charcoal (5% strength), 0.82 g of sodium carbonate and 10 mg of di-tert-butylphenol in 10 ml of dimethylacetamide for 18 hours at 170° C. The catalyst is filtered off, the mixture is diluted with dichloromethane and extracted with water. The crude product is chromatographed.

Herkunft & Nachweise