Methallyl alcohol → 4-Chloro-2-(2-methyl-2-propen-1-yloxy)nitrobenzene

HRID 440651

Reaktionsgleichung

Reaktionsgleichung von HRID 440651
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([OH:8])[CH:7]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:18][C:19](=[CH2:22])[CH2:20]O>CC(=O)CC>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([O:8][CH2:20][C:19]([CH3:22])=[CH2:18])[CH:7]=1

Komponenten

5

Edukt 3

HCID 10557Methallyl alcoholHCID 11430Potassium CarbonateHCID 11900Phenol, 5-chloro-2-nitro-

Produkt 1

HCID 224048134-Chloro-2-(2-methyl-2-propen-1-yloxy)nitrobenzeneAusbeute 84 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6569Methyl Ethyl KetoneLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

A mixture of 30.0 g (0.17 mole) of 5-chloro-2-nitrophenol, 30.49 g (0.221 mole) of potassium carbonate, and 18.47 g (0.204 mole) of 2-methyl-2-propen-1-ol in 200 mL of 2-butanone was heated at 80° C. for approximately 16 hours. During this period the reaction changed color from orange to pale yellow. At the conclusion of this period the reaction mixture was filtered, and the filtrate was evaporated under reduced pressure, leaving 32.50 g of 4-chloro-2-(2-methyl-2-propen-1-yloxy)nitrobenzene as a solid residue, m.p. 47°-49° C.

Aufarbeitung

  1. waitDuring this period the reaction changed
  2. filtrationAt the conclusion of this period the reaction mixture was filtered
  3. customthe filtrate was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-d371590700f54983b1d7d2d0dc81456b
Quelldatensatz
uspto-grants-1996_05
Patentnummer
US05521147

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