N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine → 4-(Dimethylamino)cyclohexan-1-one

HRID 440940Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 440940
C1O[C:4]2([CH2:9][CH2:8][CH:7]([N:10]([CH3:12])[CH3:11])[CH2:6][CH2:5]2)[O:3]C1>C(O)=O>[CH3:11][N:10]([CH3:12])[CH:7]1[CH2:8][CH2:9][C:4](=[O:3])[CH2:5][CH2:6]1

Komponenten

3

Edukt 1

HCID 361167N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine

Produkt 1

HCID 103745454-(Dimethylamino)cyclohexan-1-oneAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 284Formic AcidLösungsmittel

Versuchsvorschrift

4.96 gm (26.8 mMol) 4-dimethylamino-1-cyclohexanone ethylene ketal were dissolved in 50 mL formic acid and the solution stirred at reflux for 18 hours. The reaction mixture was then cooled to ambient and the volatiles removed under reduced pressure to give 3.78 gm (100%) of the title compound.

Aufarbeitung

  1. temperatureat reflux for 18 hours
  2. temperatureThe reaction mixture was then cooled to ambient and the volatiles
  3. customremoved under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-4dfc16dcbb2d4c73aea7b56866696ba8
Quelldatensatz
uspto-grants-1996_05
Patentnummer
US05521197

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