Diisopropylamine → Diisopropylammonium 2-propyl-5-thiazolecarboxylate

HRID 442494

Reaktionsgleichung

Reaktionsgleichung von HRID 442494
[CH2:1]([C:4]1[S:5][C:6]([C:9]([OH:11])=[O:10])=[CH:7][N:8]=1)[CH2:2][CH3:3].[CH:12]([NH:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13]>CC(C)=O>[CH2:1]([C:4]1[S:5][C:6]([C:9]([O-:11])=[O:10])=[CH:7][N:8]=1)[CH2:2][CH3:3].[CH:12]([NH2+:15][CH:16]([CH3:18])[CH3:17])([CH3:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 7912DiisopropylamineHCID 65773Tizoprolic Acid

Produkt 1

HCID 21415066Diisopropylammonium 2-propyl-5-thiazolecarboxylateAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

4.45 Grams of 2-propyl-5-thiazolecarboxylic acid (obtained in Example II) are dissolved in 120 cc of acetone and 2.62 gm of diisopropylamine are added. The solvent is evaporated off under low pressure and the crystals thus obtained are recrystallized from isopropyl ether. The diisopropylammonium 2-propyl-5-thiazolecarboxylate is obtained in the form of colorless crystals, soluble in water and in alcohol, melting at 120° C. (Yield: 90%).

Aufarbeitung

  1. customThe solvent is evaporated off under low pressure
  2. customthe crystals thus obtained
  3. customare recrystallized from isopropyl ether

Quellen und Nachweise

ORD-Eintrag
ord-378c935309a3447ca2cda4daca4c765c
Quelldatensatz
uspto-grants-1977_08
Patentnummer
US04045567

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