Methanol → 1H-Indole, 3-(methoxymethyl)-

HRID 443316Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 443316
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][OH:11])=[CH:2]1.[CH3:12]O>O>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH2:10][O:11][CH3:12])=[CH:2]1

Komponenten

4

Edukt 2

HCID 887Methanol3×HCID 3712Indole-3-Carbinol

Produkt 1

HCID 1544111H-Indole, 3-(methoxymethyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

Relatively pure 1H-indole-3-methanol (I3C™ from Designed Nutritional Products, Orem, UT, US) in a water solution was prepared for HPLC analysis. One sample was diluted with water and the other was diluted with methanol. By the time the partial methanol solution could be injected into the HPLC, the reaction with methanol had taken place to form 1H-indol-3-yl methoxy methane, the methyl ether of 1H-indole-3-methanol, and two peaks of about the same magnitude were observed. The same solution when diluted with water showed only one peak.

Quellen und Nachweise

ORD-Eintrag
ord-9c17ecac43234beeaadb3d6b3e14c901
Quelldatensatz
uspto-grants-1999_04
Patentnummer
US05895787

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