Acetic Acid → Perfluorophenyl acetate

HRID 446179Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 446179
[C:1]([OH:4])(=[O:3])[CH3:2].[F:5][C:6]1[C:11](O)=[C:10]([F:13])[C:9]([F:14])=[C:8]([F:15])[C:7]=1[F:16].C1(N=C=NC2CCCCC2)CCCCC1>CCOC(C)=O>[F:5][C:6]1[C:11]([O:3][C:1](=[O:4])[CH3:2])=[C:10]([F:13])[C:9]([F:14])=[C:8]([F:15])[C:7]=1[F:16]

Komponenten

5

Edukt 3

HCID 176Acetic AcidHCID 10868DicyclohexylcarbodiimideHCID 13041Pentafluorophenol

Produkt 1

HCID 87968Perfluorophenyl acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

To a 0.40 M solution of acetic acid (46 μL, 0.800 mmol) in EtOAc (2.00 mL, filtered through activated alumina) were added pentafluorophenol (162 mg, 0.880 mmol) and 1,3-dicyclohexylcarbodiimide (182 mg, 0.88 mmol). The reaction mixture was stirred for 12 h at rt at which time it was filtered (washing with EtOAc) and concentrated. Ester 19 was used immediately without further purification.

Aufarbeitung

  1. filtrationwas filtered
  2. wash(washing with EtOAc)
  3. concentrationconcentrated
  4. customEster 19 was used immediately without further purification

Quellen und Nachweise

ORD-Eintrag
ord-bbaa0589e0ef4f21b38aa3eec71002f4
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08476451B2

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