Adipic Acid → 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine;hexanedioate

HRID 449791

Reaktionsgleichung

Reaktionsgleichung von HRID 449791
[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([Cl:8])=[C:3]([C:9]2[N:14]=[N:13][C:12]([NH2:15])=[N:11][C:10]=2[NH2:16])[CH:2]=1.[C:17]([OH:26])(=[O:25])[CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23]>CO>[CH:1]1[CH:6]=[C:5]([Cl:7])[C:4]([Cl:8])=[C:3]([C:9]2[N:14]=[N:13][C:12]([NH2:15])=[N:11][C:10]=2[NH2:16])[CH:2]=1.[C:17]([O-:26])(=[O:25])[CH2:18][CH2:19][CH2:20][CH2:21][C:22]([O-:24])=[O:23]

Komponenten

4

Edukt 2

HCID 196Adipic AcidHCID 3878Lamotrigine

Produkt 1

HCID 866323226-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine;hexanedioate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

16 mg of lamotrigine was dissolved in 2 ml of methanol, 11 mg of adipic acid was added to the solution to form a single solution. The solution was then allowed to stand for several hours to effect the slow evaporation of solvent. The solids gathered were stored in screw cap vials for subsequent analysis.

Aufarbeitung

  1. customto form a single solution
  2. waitto stand for several hours
  3. customthe slow evaporation of solvent
  4. customcap vials for subsequent analysis

Quellen und Nachweise

ORD-Eintrag
ord-9374823017d143f1a784e1a60c0199c4
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08486927B2

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