Benzenamine, N,N,2-trimethyl-4-nitro- → 1-N,1-N,2-trimethylbenzene-1,4-diamine

HRID 450066Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 450066
[CH3:1][N:2]([CH3:13])[C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[CH3:12]>CO.[Pd]>[NH2:9][C:6]1[CH:7]=[CH:8][C:3]([N:2]([CH3:1])[CH3:13])=[C:4]([CH3:12])[CH:5]=1

Komponenten

4

Edukt 1

HCID 141707Benzenamine, N,N,2-trimethyl-4-nitro-

Produkt 1

HCID 4363651-N,1-N,2-trimethylbenzene-1,4-diamineAusbeute 73 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of dimethyl-(2-methyl-4-nitro-phenyl)-amine (0.49 g, 2.74 mmol) in methanol (10 ml) was hydrogenated over 10% Pd/C at 30 psi until no further gas uptake was observed. The reaction mixture was then filtered over celite and the filtrate evaporated to yield 4-amino-2-methyl-N,N-dimethyl aniline (0.3 g, 73%).

Aufarbeitung

  1. filtrationThe reaction mixture was then filtered over celite
  2. customthe filtrate evaporated

Quellen und Nachweise

ORD-Eintrag
ord-f27d90afe57948ab93ae79663c8203a4
Quelldatensatz
uspto-grants-2013_07
Patentnummer
US08486962B2

Notizen zur Reaktion

Wird geladen…