Trifluoroacetic acid → methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-1-(N-Methyl-2-(trimethylsilyl)ethoxycarbonylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propan-2-ylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate

Reaktionsgleichung

[NH2:1][C@@H:2]([CH2:15][C@H:16]1[CH2:21][CH2:20][CH2:19][O:18][CH2:17]1)[CH2:3][N:4]([CH3:14])[C:5](=[O:13])[O:6][CH2:7][CH2:8][Si:9]([CH3:12])([CH3:11])[CH3:10].CCN(C(C)C)C(C)C.C1N=CN([C:36]([N:38]2[CH:42]=N[CH:40]=[CH:39]2)=[O:37])C=1.[Cl:43][C:44]1[CH:45]=[C:46]([C@@H:50]([C@@H:59]2CCCN[CH2:60]2)[O:51][CH2:52][CH2:53][NH:54][C:55](=[O:58])[O:56][CH3:57])[CH:47]=[CH:48][CH:49]=1.C(O)(C(F)(F)F)=O>C(Cl)Cl>[Cl:43][C:44]1[CH:45]=[C:46]([C@@H:50]([C@@H:59]2[CH2:60][CH2:40][CH2:39][N:38]([C:36](=[O:37])[NH:1][C@@H:2]([CH2:15][C@H:16]3[CH2:21][CH2:20][CH2:19][O:18][CH2:17]3)[CH2:3][N:4]([C:5]([O:6][CH2:7][CH2:8][Si:9]([CH3:12])([CH3:11])[CH3:10])=[O:13])[CH3:14])[CH2:42]2)[O:51][CH2:52][CH2:53][NH:54][C:55](=[O:58])[O:56][CH3:57])[CH:47]=[CH:48][CH:49]=1