Hydrazine hydrate (1:1) → 6-hydrazinyl-N,N-dimethylpyridine-3-sulfonamide

HRID 45223Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 45223
Cl[C:2]1[N:7]=[CH:6][C:5]([S:8]([N:11]([CH3:13])[CH3:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1.O.[NH2:15][NH2:16]>CCO>[NH:15]([C:2]1[N:7]=[CH:6][C:5]([S:8]([N:11]([CH3:13])[CH3:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1)[NH2:16]

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 47298556-chloro-N,N-dimethylpyridine-3-sulfonamide

Produkt 1

HCID 52676846-hydrazinyl-N,N-dimethylpyridine-3-sulfonamideAusbeute 85,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

A mixture of 1.9 g (8.8 mmol) of 6-chloro-N,N-dimethylpyridine-3-sulfonamide and 4.6 mL (91.5 mmol) of hydrazine monohydrate in 10 mL of EtOH is heated for 2 hours at 80° C. The precipitate obtained, after cooling to room temperature, is filtered off and then washed with 10 mL of EtOH and dried under vacuum. 1.62 g of 6-hydrazino-N,N-dimethylpyridine-3-sulfonamide are obtained in the form of a white powder.

Aufarbeitung

  1. customThe precipitate obtained
  2. temperatureafter cooling to room temperature
  3. filtrationis filtered off
  4. washwashed with 10 mL of EtOH
  5. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-03e3e2556767432c8364a95b97ccb0ce
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08541455B2

Notizen zur Reaktion

Wird geladen…