Magnesium Chloride → HCID 178488035, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[CH:3]=[N:4][C:5]([CH2:11][S+:12]([O-:24])[C:13]2[N-:14][C:15]3[CH:16]=[CH:17][C:18]([O:22][CH3:23])=[CH:19][C:20]=3[N:21]=2)=[C:6]([CH3:10])[C:7]=1[O:8][CH3:9].[Na+].[Mg+2:26].[Cl-].[Cl-]>O>[CH3:1][C:2]1[CH:3]=[N:4][C:5]([CH2:11][S+:12]([O-:24])[C:13]2[N-:14][C:15]3[CH:16]=[CH:17][C:18]([O:22][CH3:23])=[CH:19][C:20]=3[N:21]=2)=[C:6]([CH3:10])[C:7]=1[O:8][CH3:9].[CH3:1][C:2]1[CH:3]=[N:4][C:5]([CH2:11][S+:12]([O-:24])[C:13]2[N-:14][C:15]3[CH:16]=[CH:17][C:18]([O:22][CH3:23])=[CH:19][C:20]=3[N:21]=2)=[C:6]([CH3:10])[C:7]=1[O:8][CH3:9].[Mg+2:26]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Esomeprazole sodium (5 g; 13.61 mmol; e.e. of 99.98%), was dissolved in DM water (63 ml) and filtered. To the filtrate, anhydrous MgCl2 (0.648 g; 6.8 mmol) dissolved in DM water (25 ml) was added drop wise and stirred for 1 h. The precipitated product was filtered, washed with DM water and dried under reduced pressure at 40° C. to yield of amorphous esomeprazole magnesium trihydrate.