Ethanol → HCID 69522445, Verbindung

HRID 456593

Reaktionsgleichung

Reaktionsgleichung von HRID 456593
Br[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[C:7]([CH:11]=1)=[N:8][S:9][N:10]=2.C(O)C.[C-:15]#[N:16].[K+]>O>[N:10]1[S:9][N:8]=[C:7]2[CH:11]=[C:3]([CH2:2][C:15]#[N:16])[CH:4]=[CH:5][C:6]=12

Komponenten

5

Edukt 3

HCID 702EthanolHCID 9032Potassium CyanideHCID 5910045-(Bromomethyl)-2,1,3-benzothiadiazole

Produkt 1

HCID 69522445HCID 69522445, VerbindungAusbeute 53,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 5-bromomethyl-benzo[1,2,5]thiadiazole [RN65858-50-6](7.0 g, 30 mmol), ethanol (50 ml)and a solution of potassium cyanide (2.3 g, 36 mmol) in water (25 ml) was stirred at 50° C. for 15 hours. The alcoholic solution was concentrated and the residue suspended in water. The solid was collected by filtration, washed with water and dried in vacuo to give benzo[1,2,5]thiadiazol-5-yl-acetonitrile (2.8 g, 47%)

Aufarbeitung

  1. concentrationThe alcoholic solution was concentrated
  2. filtrationThe solid was collected by filtration
  3. washwashed with water
  4. customdried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-a391e509cf0c4b54be8190b45336aff2
Quelldatensatz
uspto-grants-2007_03
Patentnummer
US07186730B2

Verknüpfte Notizen

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