Hydrochloric Acid → p-n-Hexylcinnamic acid

HRID 460750

Reaktionsgleichung

Reaktionsgleichung von HRID 460750
[CH2:1]([C:7]1[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].C(O)(=O)[CH2:16][C:17]([OH:19])=[O:18].Cl>N1CCCCC1.N1C=CC=CC=1>[CH2:1]([C:7]1[CH:14]=[CH:13][C:10]([CH:11]=[CH:16][C:17]([OH:19])=[O:18])=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 867Malonic AcidHCID 170813Benzaldehyde, 4-hexyl-

Produkt 1

HCID 53878923p-n-Hexylcinnamic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 8082PiperidineKatalysatorHCID 1049PyridineLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

9.4 G. of p-n-hexylbenzaldehyde in 5 ml. of absolute pyridine are treated with 5.15 g. of malonic acid and 5 drops of piperidine. Then, the mixture is heated at 100° C. for 11 hours, and, subsequently, poured on to cold aqueous hydrochloric acid and extracted with ether. The p-n-hexylcinnamic acid obtained after recrystallization of the crude product from hexane/ether has a melting point of 107°-109° C.

Aufarbeitung

  1. extractionextracted with ether

Quellen und Nachweise

ORD-Eintrag
ord-842db5c97e03421aba811d41409527b8
Quelldatensatz
uspto-grants-1977_12
Patentnummer
US04061587

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