Methyl Isocyanate → 2-Thiopheneacetonitrile, α-[[[(methylamino)carbonyl]oxy]imino]-

HRID 461014

Reaktionsgleichung

Reaktionsgleichung von HRID 461014
[N:1](=[C:3]([C:6]1[S:7][CH:8]=[CH:9][CH:10]=1)[C:4]#[N:5])[OH:2].[CH3:11][N:12]=[C:13]=[O:14]>C(N(CC)CC)C.CCOCC>[CH3:11][NH:12][C:13]([O:2][N:1]=[C:3]([C:6]1[S:7][CH:8]=[CH:9][CH:10]=1)[C:4]#[N:5])=[O:14]

Komponenten

5

Edukt 2

HCID 12228Methyl IsocyanateHCID 73667355Alpha-Oximino-2-Thienylacetonitrile

Produkt 1

HCID 544692302-Thiopheneacetonitrile, α-[[[(methylamino)carbonyl]oxy]imino]-

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 8471TriethylamineKatalysatorHCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

To a solution of 3.04 g. (0.02 mole) of alphaoximino-2-thienylacetonitrile and 2 drops of triethylamine in 50 ml. of ether was added 1.14 g. (0.02 mole) of methylisocyanate in 10 ml. of ether. After 1 hour the solid was filtered and crystallized from benzene to give 3.8 g. of product melting at 154°-155° C.

Aufarbeitung

  1. filtrationAfter 1 hour the solid was filtered
  2. customcrystallized from benzene
  3. customto give 3.8 g

Quellen und Nachweise

ORD-Eintrag
ord-867d5ad1b26e43df92c8a83a35b5e159
Quelldatensatz
uspto-grants-1977_12
Patentnummer
US04061764

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