N-(4-nitrophenyl)pentanamide → N-(4-aminophenyl)pentanamide

HRID 461019

Reaktionsgleichung

Reaktionsgleichung von HRID 461019
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:15][CH:16]=1

Komponenten

4

Edukt 1

HCID 3762929N-(4-nitrophenyl)pentanamide

Produkt 1

HCID 1725711N-(4-aminophenyl)pentanamide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 4'-nitrovaleranilide (13.33 g., 0.06 mole) in absolute ethanol (750 ml.) is hydrogenated over 10% palladium on charcoal (2 g.) until the theoretical absorption is achieved. The catalyst is removed and the solvent is removed in vacuo. The residue is recrystallized from butyl chloride to yield 9.0 g., m.p. 81°-83° C.

Aufarbeitung

  1. customThe catalyst is removed
  2. customthe solvent is removed in vacuo
  3. customThe residue is recrystallized from butyl chloride
  4. customto yield 9.0 g

Quellen und Nachweise

ORD-Eintrag
ord-1657976fc8b14bb1ae6485729ff31a32
Quelldatensatz
uspto-grants-1977_12
Patentnummer
US04061763

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