Nitric Acid → HCID 54734201, Verbindung

HRID 462068Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 462068
[N+:1]([O-:4])(O)=[O:2].[CH2:5]([N:7]1[C:17]2[C:12](=[CH:13][C:14]([CH3:18])=[CH:15][CH:16]=2)[C:11]([OH:19])=[CH:10][C:8]1=[O:9])[CH3:6]>C(O)(=O)C>[CH2:5]([N:7]1[C:17]2[C:12](=[CH:13][C:14]([CH3:18])=[CH:15][CH:16]=2)[C:11]([OH:19])=[C:10]([N+:1]([O-:4])=[O:2])[C:8]1=[O:9])[CH3:6]

Komponenten

4

Edukt 2

HCID 944Nitric AcidHCID 546963011-Ethyl-4-hydroxy-6-methylquinolin-2(1H)-one

Produkt 1

HCID 54734201HCID 54734201, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

Concentrated nitric acid (2.5 ml; d, 1.42) was added to a suspension of 1-ethyl-4-hydroxy-6-methyl carbostyril. (1.82g; 0.009 mole) in glacial acetic acid (10 ml) and the mixture warmed to 100° C. The solid dissolved and the 3-nitro derivative immediately solidified as a yellow solid. After cooling the solid was filtered, washed well with water and dried in vacuo over P2O5, m.p. 192°-4° C; (Found; C, 58.16; H, 5.02; N, 11.29; C12H12N2O4 requires; C, 58.06; H, 4.87; N, 11.29%).

Aufarbeitung

  1. dissolutionThe solid dissolved
  2. temperatureAfter cooling the solid
  3. filtrationwas filtered
  4. washwashed well with water
  5. dry with materialdried in vacuo over P2O5, m.p. 192°-4° C

Quellen und Nachweise

ORD-Eintrag
ord-6b6b0506a15a4aceae6c2355348e2508
Quelldatensatz
uspto-grants-1977_12
Patentnummer
US04065457

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