HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen Cyanide → 2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen Cyanide | HCID 768 | — |
| Edukt | Isobutyraldehyde | HCID 6561 | — |
| Edukt | 2-Chloro-4-trifluoromethylaniline | HCID 162001 | — |
| Edukt | 2-Fluoro-4-(trifluoromethyl)aniline | HCID 2737674 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile | HCID 20283984 | — |
Reaktionsschritte
Following the procedure of Example 1, each of 3-chloro-4-aminobenzotrifluoride and 3-fluoro-4-aminobenzotrifluoride is reacted with hydrogen cyanide and isobutyraldehyde, in a neat, initially water-free system, to give the respective nitrile, 2-(2-chloro-4-trifluoro-methylphenylamino)-3-methylbutyronitrile and 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04517130 |
| Quelldatensatz | uspto-grants-1985_05 |
| ORD ID | ord-f4fb8e7036e843d7865338e8ca199b44 |
| Quellennotiz | uspto-grants-1985_05 |