Aluminum Stearate → Xylometazoline

HRID 463507

Reaktionsgleichung

Reaktionsgleichung von HRID 463507
C([O-])(=O)CCCCCCCCCCCCCCCCC.[Al+3].C([O-])(=O)CCCCCCCCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCCCCCCCC.[CH3:62][C:63]1[CH:64]=[C:65]([C:76]([CH3:79])([CH3:78])[CH3:77])[CH:66]=[C:67]([CH3:75])[C:68]=1[CH2:69][C:70]1[NH:74][CH2:73][CH2:72][N:71]=1.Cl>>[CH3:75][C:67]1[CH:66]=[C:65]([C:76]([CH3:79])([CH3:78])[CH3:77])[CH:64]=[C:63]([CH3:62])[C:68]=1[CH2:69][C:70]1[NH:74][CH2:73][CH2:72][N:71]=1

Komponenten

3

Edukt 2

HCID 12496Aluminum StearateHCID 5282386Xylometazoline Hydrochloride

Produkt 1

HCID 5709Xylometazoline

Reaktionsbedingungen

Temperatur
115 °C

Versuchsvorschrift

The aluminium stearate was dispersed with stirring in a portion of the sunflower oil heated to 115° C. The dispersion was added to the rest of the sunflower oil heated to 140° C. The gel was stirred at 130° C. for 15 minutes and then allowed to cool without stirring to room temperature. The milled xylometazoline hydrochloride was dispersed in the cooled gel base and then passed through a colloid mill to produce a fine, homogenous dispersion. The dispersion was filled into plastic bottles fitted with a dosing pump.

Aufarbeitung

  1. additionThe dispersion was added to the rest of the sunflower oil
  2. temperatureheated to 140° C
  3. stirringThe gel was stirred at 130° C. for 15 minutes
  4. temperatureto cool
  5. stirringwithout stirring to room temperature
  6. customto produce a fine, homogenous dispersion
  7. additionThe dispersion was filled into plastic bottles
  8. customfitted with a dosing pump

Quellen und Nachweise

ORD-Eintrag
ord-73a4f717c1554612a54dd4a8b779389e
Quelldatensatz
uspto-grants-1985_05
Patentnummer
US04520014

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