2,3-Dichloroquinoxaline → 2-Chloro-3-hydrazinoquinoxaline

HRID 464279

Reaktionsgleichung

Reaktionsgleichung von HRID 464279
[Cl:1][C:2]1[C:11](Cl)=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.O.[NH2:14][NH2:15]>C(O)C>[Cl:1][C:2]1[C:11]([NH:14][NH2:15])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1

Komponenten

4

Edukt 2

HCID 166592,3-DichloroquinoxalineHCID 24654Hydrazine hydrate (1:1)

Produkt 1

HCID 36588202-Chloro-3-hydrazinoquinoxalineAusbeute 41 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

2,3-Dichloroquinoxaline (33.5 g., 0.168 mole) was stirred with hydrazine hydrate (18.5 g., 0.369 mole) in 500 ml. of ethanol at room temperature overnight (i.e.. at ca. 20° C. for approximately 16 hours). The thick, yellow slurry was filtered and the precipitate was washed with ethanol. The precipitated material was recrystallized from hot methanol to give 13.5 g. (41% yield) of 2-chloro-3-hydrazinoquinoxaline, m.p. 181° C. (decomp.). Mass spectrum: m/e, 194 (P).

Aufarbeitung

  1. customat room temperature
  2. customovernight (i.e.. at ca. 20° C. for approximately 16 hours)
  3. filtrationThe thick, yellow slurry was filtered
  4. washthe precipitate was washed with ethanol
  5. customThe precipitated material was recrystallized from hot methanol
  6. customto give 13.5 g

Quellen und Nachweise

ORD-Eintrag
ord-a221652dd3ff4eb0a45c35470f69b1ee
Quelldatensatz
uspto-grants-1985_10
Patentnummer
US04547501

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