Reaktionsgleichung
[C:1](O)(=O)[CH2:2][CH3:3].[NH2:6][C:7]1[C:12]([NH2:13])=[C:11]([CH3:14])[CH:10]=[CH:9][N:8]=1>>[CH2:2]([C:1]1[NH:13][C:12]2[C:7]([N:6]=1)=[N:8][CH:9]=[CH:10][C:11]=2[CH3:14])[CH3:3]Komponenten
3
Reaktionsbedingungen
- Temperatur
- 100 °C
Versuchsvorschrift
A mixture of propionic acid (0.89 ml, 12 mmols), 2,3-diamino-4-picoline (1.23 g, 10 mmol) and polyphosphoric acid (40 g) was heated to 100° C. for 6 hours. Work-up of the reaction and purification of the crude product according to the procedure described in Step 1 of Example 9 gave the desired compound (1.46 g, 90%) as a tan colored solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-36c648157a574f4e940fc5cd20b849e4
- Quelldatensatz
- uspto-grants-1992_10
- Patentnummer
- US05157026
Verknüpfte Notizen
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