Hydrochloric Acid → 2-Cyclohexylacetaldehyde

HRID 467271

Reaktionsgleichung

Reaktionsgleichung von HRID 467271
C[O:2][CH:3](OC)[CH2:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.Cl>O1CCCC1.C(OCC)C>[CH:5]1([CH2:4][CH:3]=[O:2])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 11052116Cyclohexylacetaldehyde dimethyl acetal

Produkt 1

HCID 3166272-CyclohexylacetaldehydeAusbeute 131,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

To a solution of 60 gm (349 mMol) cyclohexylacetaldehyde dimethyl acetal in tetrahydrofuran (50 ml) and diethyl ether (100 ml) was added 1N hydrochloric acid (200 ml) and the resulting mixture was stirred for 2.5 hours at room temperature. The reaction mixture was then partitioned between diethyl ether and water. The ether layer was then separated, dried over magnesium sulfate and concentrated under reduced pressure to give 58 gm of crude cyclohexylacetaldehyde.

Aufarbeitung

  1. customThe reaction mixture was then partitioned between diethyl ether and water
  2. customThe ether layer was then separated
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-6041e0a3e87a40dd9d934a4c8934152b
Quelldatensatz
uspto-grants-1992_10
Patentnummer
US05159081

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