Iodine → HCID 12786936, Verbindung

HRID 468970Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 468970
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([Br:10])[N:5]=1)(=[O:3])[CH3:2].[I:11]I.[N:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[I-:11].[Br:10][C:6]1[N:5]=[C:4]([C:1](=[O:3])[CH2:2][N+:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:9]=[CH:8][CH:7]=1

Komponenten

5

Edukt 3

HCID 807IodineHCID 1049PyridineHCID 112985782-Acetyl-6-bromopyridine

Produkt 1

HCID 12786936HCID 12786936, VerbindungAusbeute 62 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

A reaction vessel was charged with 11.0 g of 2-acetyl-6-bromopyridine, 14.0 g of iodine, and 45 mL of pyridine, followed by heating and stirring at 100° C. for 5 hours. After cooling to room temperature, 100 mL of water was added thereto and purification by recrystallization was performed. The reaction product was vacuum-dried at 70° C. for 12 hours to obtain 13.8 g (yield, 62%) of [2-(6-bromopyridin-2-yl)oxoethyl]pyridinium iodide as a brown powder.

Aufarbeitung

  1. temperatureby heating
  2. temperatureAfter cooling to room temperature
  3. custompurification
  4. customby recrystallization
  5. customThe reaction product was vacuum-dried at 70° C. for 12 hours

Quellen und Nachweise

ORD-Eintrag
ord-e56afeb4cc484ae39d9c458df65c9bf0
Quelldatensatz
uspto-grants-2014_01
Patentnummer
US08624228B2

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