Phenol → 4-Hydroxyphenylglycine
Reaktionsgleichung
[C:1]([O-:5])(=[O:4])[CH:2]=O.[Na+].C([O-])(=O)C.[NH4+:11].[C:12]1([OH:18])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>O>[CH:14]1[C:15]([CH:2]([NH2:11])[C:1]([OH:5])=[O:4])=[CH:16][CH:17]=[C:12]([OH:18])[CH:13]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
36.9 g of sodium glyoxylate are added to 130 ml of water, and 75 g of ammonium acetate and 60 g of phenol are added thereto under stirring. The mixture is stirred at 30° to 35° C. for 48 hours. After the reaction, the crystalline precipitates are collected by filtration under cooling, and then successively washed with water and methanol. 27.2 g of DL-p-hydroxyphenylglycine are thereby obtained as white crystals.
Aufarbeitung
- additionare added
- stirringThe mixture is stirred at 30° to 35° C. for 48 hours
- customAfter the reaction
- customthe crystalline precipitates
- filtrationare collected by filtration
- temperatureunder cooling
- washsuccessively washed with water and methanol
Quellen und Nachweise
- ORD-Eintrag
- ord-2949a0b371134340828328edc977af50
- Quelldatensatz
- uspto-grants-1979_11
- Patentnummer
- US04175206
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