Ethyl o-cyanomethylcinnamate → Ethyl o-(cyanomethyl)hydrocinnamate

HRID 46989

Reaktionsgleichung

Reaktionsgleichung von HRID 46989
[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2].[H][H]>C(O)C.[Pd]>[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2]

Komponenten

5

Edukt 2

HCID 53697120Ethyl o-cyanomethylcinnamateHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 54486935Ethyl o-(cyanomethyl)hydrocinnamate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

Ethyl o-(cyanomethyl)cinnamate (75.1 g., 0.35 mole) is dissolved in ethanol (300 ml.) and hydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g. of a 5% palladium on charcoal catalyst. When the theoretical amount of hydrogen (0.35 mole) has been absorbed, the catalyst is filtered off and the ethanol removed by distillation at reduced pressure to yield ethyl o-(cyanomethyl)hydrocinnamate.

Aufarbeitung

  1. customhydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g
  2. filtrationthe catalyst is filtered off
  3. customthe ethanol removed by distillation at reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5a2238bf2cb243deb54f41fa66ed13b8
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04175203

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