Hydrochloric Acid → 1-(2-Mercaptomethyl-3-mercaptopropanoyl)-L-proline

HRID 47128Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 47128
C([S:4][CH2:5][CH:6]([CH2:17][S:18]C(=O)C)[C:7]([N:9]1[CH2:16][CH2:15][CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.Cl>O.N>[SH:4][CH2:5][CH:6]([CH2:17][SH:18])[C:7]([N:9]1[CH2:16][CH2:15][CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8]

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 13145535(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline

Produkt 1

HCID 131455371-(2-Mercaptomethyl-3-mercaptopropanoyl)-L-proline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 222AmmoniaLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

1-[(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline (1.2 g.) is dissolved in a mixture of water (12 ml.) and concentrated ammonia (12 ml.) under an atmosphere of argon. After twenty minutes, the mixture is acidified with concentrated hydrochloric acid. The crystalline precipitate 1-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered and dried, yield 0.63 g., m.p. 138°-140°.

Aufarbeitung

  1. waitAfter twenty minutes
  2. filtrationThe crystalline precipitate 1-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-43806bf1c4eb4b53b1e20147dc65efec
Quelldatensatz
uspto-grants-1979_11
Patentnummer
US04176235

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