HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Iodosuccinimide → 5-Iodo-6-(trifluoromethyl)pyridin-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-Iodosuccinimide | HCID 120273 | — |
| Edukt | 2-Amino-6-(trifluoromethyl)pyridine | HCID 821024 | — |
| Produkt | 5-Iodo-6-(trifluoromethyl)pyridin-2-amine | HCID 58073065 | — |
Reaktionsschritte
The title compound is synthesized according to general procedure GP1 starting from 4.8 g (30 mmol) 6-trifluoromethyl-pyridin-2-ylamine and 6.7 g (30 mmol) NIS. Yield after precipitation from the reaction mixture and isolation of additional product from the mother liquid by chromatography in silica gel: 5.73 g (67%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08633183B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-e63083d2adb44062b01f7509973f862e |
| Quellennotiz | uspto-grants-2014_01 |