Sodium Nitrate → 4-Bromo-3-nitrobenzaldehyde

HRID 478288

Reaktionsgleichung

Reaktionsgleichung von HRID 478288
[N+:1]([O-:4])([O-])=[O:2].[Na+].[Br:6][C:7]1[CH:14]=[CH:13][C:10]([CH:11]=[O:12])=[CH:9][CH:8]=1>S(=O)(=O)(O)O>[Br:6][C:7]1[CH:14]=[CH:13][C:10]([CH:11]=[O:12])=[CH:9][C:8]=1[N+:1]([O-:4])=[O:2]

Komponenten

4

Edukt 2

HCID 24268Sodium NitrateHCID 707414-Bromobenzaldehyde

Produkt 1

HCID 8087924-Bromo-3-nitrobenzaldehydeAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Reaktionsbedingungen

Temperatur
10 °C

Versuchsvorschrift

A suspension of sodium nitrate (1.37 g, 16.2 mmol) in concentrated sulfuric acid (15 mL) was stirred at 10° C. until a homogeneous solution was obtained. The solution was treated with 4-bromobenzaldehyde (2.50 g, 13.5 mmol) in portionwise fashion over a 20 minute period. The solution was poured onto ice (50 g) and the resulting pale yellow precipitate was collected by filteration. The precipitate was washed with copious amounts of water then dried at 30° C. under reduced pressure to provide the title compound as a pale yellow solid (2.95 g, 12.8 mmol, 95%).

Aufarbeitung

  1. customwas obtained
  2. additionThe solution was poured onto ice (50 g)
  3. customthe resulting pale yellow precipitate was collected by filteration
  4. washThe precipitate was washed with copious amounts of water
  5. customthen dried at 30° C. under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-795925d01a8d41a0be58dadcd0128125
Quelldatensatz
uspto-grants-2003_11
Patentnummer
US06642222B2

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