Oxalyl chloride → HCID 22609552, Verbindung

HRID 479396Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 479396
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[CH3:7][O:8][C:9]1[CH:10]=[C:11](/[CH:19]=[CH:20]/[CH:21]=C/C(O)=O)[CH:12]=[C:13]([O:17][CH3:18])[C:14]=1[O:15][CH3:16]>CN(C)C=O.C(Cl)Cl>[CH3:18][O:17][C:13]1[CH:12]=[C:11](/[CH:19]=[CH:20]/[CH:21]=[CH:1]/[C:2]([Cl:4])=[O:3])[CH:10]=[C:9]([O:8][CH3:7])[C:14]=1[O:15][CH3:16]

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 15257506HCID 15257506, Verbindung

Produkt 1

HCID 22609552HCID 22609552, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 22350042dichloromethane N,N-dimethylformamideLösungsmittel

Versuchsvorschrift

After oxalyl chloride (0.055 ml; 0.63 mmol) was added to a solution of (E,E)-5-(3,4,5-trimethoxyphenyl)-2,4-pentadienoic acid (116 mg; 0.44 mmol) in dimethylformamide-methylene chloride (0.1 ml-5 ml) under ice cooling. The ice bath was removed, and the mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated under reduced pressure to obtain crude crystals of (E,E)-5-(3,4,5-trimethoxyphenyl)-2,4-pentadienoyl chloride.

Aufarbeitung

  1. customThe ice bath was removed
  2. concentrationThe reaction mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-067ffdec0e5c4b5dbea8b69c9d48d5c4
Quelldatensatz
uspto-grants-2003_11
Patentnummer
US06645957B2

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