Potassium Iodide → HCID 19063054, Verbindung

HRID 482509

Reaktionsgleichung

Reaktionsgleichung von HRID 482509
[C:1]12([C:11]3[CH:12]=[C:13]([C:18]#[C:19][C:20]4[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=4)[CH:14]=[CH:15][C:16]=3[OH:17])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.Br[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][OH:37].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(=O)CC>[C:1]12([C:11]3[CH:12]=[C:13]([C:18]#[C:19][C:20]4[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=4)[CH:14]=[CH:15][C:16]=3[O:17][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][OH:37])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Komponenten

6

Edukt 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 779706-Bromo-1-hexanolHCID 19063002Methyl 4-[3-(1-adamantyl)-4-hydroxyphenylethynyl]benzoate

Produkt 1

HCID 19063054HCID 19063054, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6569Methyl Ethyl KetoneLösungsmittel

Versuchsvorschrift

2 g (5.1 mmol) of methyl 4-[3-(1-adamantyl)-4-hydroxyphenylethynyl]benzoate, 1.1 ml (8.3 mmol) of 6-bromo-1-hexanol, 1.2 g (8.8 mmol) of potassium carbonate, 20 mg of potassium iodide and 100 ml of 2-butanone were introduced into a round-bottomed flask. The reaction mixture was heated at reflux for twelve hours and was evaporated to dryness, the residue was taken up in water and ethyl acetate and the organic phase was separated by settling, dried over magnesium sulfate and evaporated.

Aufarbeitung

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux for twelve hours
  3. customwas evaporated to dryness
  4. customethyl acetate and the organic phase was separated
  5. dry with materialdried over magnesium sulfate
  6. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-8e979760d5ce490b8ea450be9f2e774b
Quelldatensatz
uspto-grants-1998_08
Patentnummer
US05798354

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