Acetic Anhydride → Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)-

HRID 483643

Reaktionsgleichung

Reaktionsgleichung von HRID 483643
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][CH2:8][CH2:7]2)([O-:3])=[O:2].[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[C:13]([N:9]1[C:10]2[C:6](=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:12][CH:11]=2)[CH2:7][CH2:8]1)(=[O:15])[CH3:14]

Komponenten

4

Edukt 2

HCID 7918Acetic AnhydrideHCID 362195-Nitroindoline

Produkt 1

HCID 36566Ethanone, 1-(2,3-dihydro-5-nitro-1H-indol-1-yl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

A mixture of 5-nitroindoline (I, 12.012 g) in pyridine (100ml) and acetic anhydride (50 ml) is stirred for 17 hr under argon. The mixture is then concentrated under reduced pressure to give the title compound, mp 175°-177°; NMR (CDCl3, 300 MHz) 8.28, 8.10, 8.01, 4.23, 3.31 and 2.28 δ; CMR (CDCl3, 75.47 MHz) 23.95, 27.01, 49.11, 115.73, 119.93, 124.27, 132.4, 143.4 and 169.8 δ; IR (CHCl3) 1680, 1600, 1480, 1470, 1390, 1340 and 1320 cm-1.

Aufarbeitung

  1. concentrationThe mixture is then concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-bf14d97a85834bd986d21199293f3abb
Quelldatensatz
uspto-grants-1993_07
Patentnummer
US05225565

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