Sulfolane → 2,4-Difluorobenzaldehyde

HRID 483908

Reaktionsgleichung

Reaktionsgleichung von HRID 483908
Cl[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[C:4]([F:10])[CH:3]=1.ClC1C=C([F:20])C=CC=1C=O.S1(CCCC1)(=O)=O.[F-].[K+]>>[F:10][C:4]1[CH:3]=[C:2]([F:20])[CH:9]=[CH:8][C:5]=1[CH:6]=[O:7]

Komponenten

5

Edukt 4

HCID 31347SulfolaneHCID 1450242-Chloro-4-fluorobenzaldehydeHCID 522689Potassium FluorideHCID 27249084-Chloro-2-fluorobenzaldehyde

Produkt 1

HCID 737702,4-Difluorobenzaldehyde

Versuchsvorschrift

158.5 g (1 mol) of a mixture of 56% of 4-chloro-2-fluoro-benzaldehyde and 44% of 2-chloro-4-fluorobenzaldehyde were heated together with 700 g of sulfolane and 75 g (1.29 mol) of potassium fluoride at 215° C. for 10 h. The working up was carried out as in Example 1. 99.5 g of 2,4-difluorobenzaldehyde equivalent to 70% of the feed-stock was obtained.

Quellen und Nachweise

ORD-Eintrag
ord-6c1a97fab7104349a0387170691bc375
Quelldatensatz
uspto-grants-1993_07
Patentnummer
US05227531

Verknüpfte Notizen

Wird geladen…