1,8-Octanediamine, 4-(aminomethyl)- → 1,8-Bis(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]amino)-4-(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]aminomethyl)octane

HRID 484947Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 484947
Cl[C:2]1[N:7]=[C:6]([NH:8][CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]2)[N:5]=[C:4]([NH:19][CH:20]2[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23][C:22]([CH3:29])([CH3:28])[CH2:21]2)[N:3]=1.[NH2:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:40][NH2:41])[CH2:35][CH2:36][CH2:37][CH2:38][NH2:39]>O>[CH3:28][C:22]1([CH3:29])[CH2:21][CH:20]([NH:19][C:4]2[N:5]=[C:6]([NH:8][CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:18])([CH3:17])[CH2:10]3)[N:7]=[C:2]([NH:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:40][NH:41][C:2]3[N:7]=[C:6]([NH:8][CH:9]4[CH2:14][C:13]([CH3:16])([CH3:15])[NH:12][C:11]([CH3:17])([CH3:18])[CH2:10]4)[N:5]=[C:4]([NH:19][CH:20]4[CH2:25][C:24]([CH3:26])([CH3:27])[NH:23][C:22]([CH3:28])([CH3:29])[CH2:21]4)[N:3]=3)[CH2:35][CH2:36][CH2:37][CH2:38][NH:39][C:2]3[N:3]=[C:4]([NH:19][CH:20]4[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23][C:22]([CH3:29])([CH3:28])[CH2:21]4)[N:5]=[C:6]([NH:8][CH:9]4[CH2:10][C:11]([CH3:18])([CH3:17])[NH:12][C:13]([CH3:16])([CH3:15])[CH2:14]4)[N:7]=3)[N:3]=2)[CH2:25][C:24]([CH3:27])([CH3:26])[NH:23]1

Komponenten

4

Edukt 2

HCID 942111,8-Octanediamine, 4-(aminomethyl)-HCID 214680172-Chloro-4,6-bis(2,2,6,6-tetramethyl-4-piperidylamino)-1,3,5-triazine

Produkt 1

HCID 202721371,8-Bis(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]amino)-4-(N-[2,4-bis(2,2,6,6-tetramethylpiperid-4-ylamino)-1,3,5-triazin-6-yl]aminomethyl)octane

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

5.1 g of 2-chloro-4,6-bis[N-(2,2,6,6-tetramethyl-4-piperidyl)amino]-1,3,5-triazine [prepared as described in Preparation 9(b)] were reacted with 0.7 g of 1,8-diamino-4-aminomethyloctane, following the procedure described in Example 9. After completion of the reaction, the reaction mixture was poured into water and extracted with chloroform. The extract was dried over anhydrous potassium carbonate, and the solvent was distilled off. The residue was purified by column chromatography through silica gel, eluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine, to give the desired Compound No. 1 in the form of crystals melting at 148°-158° C.

Aufarbeitung

  1. customAfter completion of the reaction
  2. extractionextracted with chloroform
  3. dry with materialThe extract was dried over anhydrous potassium carbonate
  4. distillationthe solvent was distilled off
  5. customThe residue was purified by column chromatography through silica gel
  6. washeluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine

Quellen und Nachweise

ORD-Eintrag
ord-1ea1e17b3bb245cf80c2b46ec1cd01fe
Quelldatensatz
uspto-grants-1985_08
Patentnummer
US04533688

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