Water → 3-(Phenyliminomethyl)dibenzo[b,f]thiepin-5,5-dioxide

HRID 485110Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 485110
[CH:1]1[C:11]2[CH:10]=[CH:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[S:6](=[O:17])(=[O:16])[C:5]=2[CH:4]=[C:3]([CH:18]=O)[CH:2]=1.[NH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.O>C1(C)C=CC=CC=1>[C:21]1([N:20]=[CH:18][C:3]2[CH:2]=[CH:1][C:11]3[CH:10]=[CH:9][C:8]4[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=4[S:6](=[O:17])(=[O:16])[C:5]=3[CH:4]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 6115AnilineHCID 13520245Dibenzo[b,f]thiepin-3-carboxaldehyde 5,5-dioxide

Produkt 1

HCID 202715043-(Phenyliminomethyl)dibenzo[b,f]thiepin-5,5-dioxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Heat a mixture of 675 mg (2.5 mmoles) of dibenzo[b,f]thiepin-3-carboxaldehyde-5,5-dioxide and 465 mg of aniline (5 mmoles) in 20 ml of toluene, under reflux, with azetropic removal of water for 21 hours. Cool the mixture and filter the insoluble product. Stir the solid in 10 ml of ether containing a few drops of THF for 10 minutes then filter to obtain the pure product, 704 mg, mp: 184°-185°.

Aufarbeitung

  1. temperatureHeat
  2. temperatureCool the mixture
  3. filtrationfilter the insoluble product
  4. filtrationthen filter
  5. customto obtain the pure product, 704 mg, mp: 184°-185°

Quellen und Nachweise

ORD-Eintrag
ord-54cc05676c3b4bd795500ef9ec0ae011
Quelldatensatz
uspto-grants-1985_08
Patentnummer
US04535171

Notizen zur Reaktion

Wird geladen…