Potassium Iodide → N-[[4-bromo-3-[1-(diallylcarbamoyl)ethoxy]phenyl]]-3,4,5,6-tetrahydrophthalimide

HRID 485214

Reaktionsgleichung

Reaktionsgleichung von HRID 485214
[CH2:1]([N:4]([CH2:10][CH:11]=[CH2:12])[C:5](=[O:9])[CH:6](Br)[CH3:7])[CH:2]=[CH2:3].[Br:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]2[C:24](=[O:25])[C:23]3[CH2:26][CH2:27][CH2:28][CH2:29][C:22]=3[C:21]2=[O:30])=[CH:16][C:15]=1[OH:31].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(C)=O>[Br:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]2[C:21](=[O:30])[C:22]3[CH2:29][CH2:28][CH2:27][CH2:26][C:23]=3[C:24]2=[O:25])=[CH:16][C:15]=1[O:31][CH:6]([C:5](=[O:9])[N:4]([CH2:1][CH:2]=[CH2:3])[CH2:10][CH:11]=[CH2:12])[CH3:7]

Komponenten

6

Edukt 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 12769237N-(4-bromo-3-hydroxyphenyl)-3,4,5,6-tetrahydrophthalimideHCID 13036601N,N-diallyl alpha-bromopropionamide

Produkt 1

HCID 13503503N-[[4-bromo-3-[1-(diallylcarbamoyl)ethoxy]phenyl]]-3,4,5,6-tetrahydrophthalimide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

The reaction mixture was washed with water and dried and the solvent was distilled off to obtain 3.8 g. of N,N-diallyl α-bromopropionamide. The product was admixed with 3.5 g. of N-(4-bromo-3-hydroxyphenyl)-3,4,5,6-tetrahydrophthalimide, 2.2 g. of potassium carbonate, 1.8 g. of potassium iodide and 50 ml. of acetone.

Aufarbeitung

  1. washThe reaction mixture was washed with water
  2. customdried
  3. distillationthe solvent was distilled off
  4. customto obtain 3.8 g

Quellen und Nachweise

ORD-Eintrag
ord-bf2d6795dd0b49899e460acfaecd3e6b
Quelldatensatz
uspto-grants-1985_08
Patentnummer
US04536209

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