Methylamine → 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene N-methylsulfenamide

HRID 485620Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 485620
[CH3:1][NH2:2].[Cl:3][C:4]1[CH:21]=[C:20]([C:22]([F:25])([F:24])[F:23])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([S:16]Cl)[C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=1>CCOCC>[Cl:3][C:4]1[CH:21]=[C:20]([C:22]([F:23])([F:25])[F:24])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=1.[CH3:1][NH:2][SH:16]

Komponenten

4

Edukt 2

HCID 6329MethylamineHCID 13246608HCID 13246608, Verbindung

Produkt 1

HCID 867402683-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene N-methylsulfenamideAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

3.1 g of methylamine in the form of a 40% strength aqueous solution were added to a solution of 19.2 parts by weight of 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzenesulfenyl chloride in 100 parts by volume of ether, and stirring was continued for a further 2 hours at room temperature. The organic phase was separated off, dried with magnesium sulfate, filtered, and evaporated down under reduced pressure. 17.5 parts by weight (95% yield) of 3-(2'-chloro-4'-trifluoromethylphenoxy)-6-nitrobenzene-N-methylsulfenamide of refractive index nD25 : 1.6109 were obtained (compound No. 5).

Aufarbeitung

  1. customThe organic phase was separated off
  2. dry with materialdried with magnesium sulfate
  3. filtrationfiltered
  4. customevaporated down under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-92db66c6937445a49868ecfa2e625f80
Quelldatensatz
uspto-grants-1985_08
Patentnummer
US04537621

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