HCID 13338728, Verbindung → HCID 13338729, Verbindung

HRID 485667Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 485667
C(O[CH:5]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[NH:11][C:10](=[O:18])[CH2:9][CH2:8][CH2:7][CH2:6]1)(=O)C>C(O)C.[Pd]>[NH:11]1[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1=[O:18]

Komponenten

4

Edukt 1

HCID 13338728HCID 13338728, Verbindung

Produkt 1

HCID 13338729HCID 13338729, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 7-acetoxy-1,3,4,5,6,7-hexahydro-1-benzazonin-2-one (7.4 g) in ethanol (250 ml) is hydrogenated at 3 atmospheres at 70° using 10% palladium on charcoal (1.5 g) as catalyst. The catalyst is filtered off and the solvent removed under reduced pressure. The residue is recrystallized to give 1,3,4,5,6,7-hexahydro-1-benzazonin-2-one.

Aufarbeitung

  1. customis hydrogenated at 3 atmospheres at 70°
  2. filtrationThe catalyst is filtered off
  3. customthe solvent removed under reduced pressure
  4. customThe residue is recrystallized

Quellen und Nachweise

ORD-Eintrag
ord-ea058813055040c4a405167c18fcf9a0
Quelldatensatz
uspto-grants-1985_08
Patentnummer
US04537885

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