Carbon Dioxide → HCID 178447888, Verbindung

HRID 493046Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 493046
[Mg].[CH2:2]([C@H:5]1[CH2:10][CH2:9][C@H:8]([C:11]2[CH:16]=[CH:15][C:14](Br)=[CH:13][CH:12]=2)[CH2:7][CH2:6]1)[CH2:3][CH3:4].[C:18](=[O:20])=[O:19].Cl>O1CCCC1>[CH2:2]([C@H:5]1[CH2:10][CH2:9][C@H:8]([C:11]2[CH:16]=[CH:15][C:14]([C:18]([OH:20])=[O:19])=[CH:13][CH:12]=2)[CH2:7][CH2:6]1)[CH2:3][CH3:4]

Komponenten

6

Edukt 4

HCID 280Carbon Dioxide2×HCID 313Hydrochloric AcidHCID 5462224MagnesiumHCID 178447827HCID 178447827, Verbindung

Produkt 1

HCID 178447888HCID 178447888, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A Grignard reagent was prepared from a solution of 50 ml of dried tetrahydrofuran in which 0.88 g (36.7 mmol) of magnesium and 10.0 g (35.6 mmol) of 1-(trans-4-n-propylcyclohexyl)-4-bromobenzene were dissolved, and the Grignard reagent was put into dry ice. After vaporizing the dry ice, hydrochloric acid was added to the resultant to give a precipitate, and the precipitate was filtered, washed with water, dried, and recrystallized from toluene to give 7.5 g (30.5 mmol) of p-(trans-4-propylcyclohexyl)benzoic acid.

Aufarbeitung

  1. dissolutionwere dissolved
  2. additionwas added to the resultant
  3. customto give a precipitate
  4. filtrationthe precipitate was filtered
  5. washwashed with water
  6. customdried
  7. customrecrystallized from toluene

Quellen und Nachweise

ORD-Eintrag
ord-dc817312d04a44abad769452b9f32f8e
Quelldatensatz
uspto-grants-2009_05
Patentnummer
US07534547B2

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