Tetrabutylammonium Fluoride → HCID 69928788, Verbindung

HRID 49348Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 49348
[CH2:1](/[C:3](/[C:20]1[S:24][CH:23]=[C:22]([CH2:25][O:26][C:27]2[CH:28]=[C:29]([C:37]([O:39][CH3:40])=[O:38])[C:30](=[CH:35][CH:36]=2)[C:31]([O:33][CH3:34])=[O:32])[CH:21]=1)=[CH:4]\[CH2:5][CH2:6][C:7]([CH2:18][CH3:19])([O:10][Si](CC)(CC)CC)[CH2:8][CH3:9])[CH3:2].[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[CH2:1](/[C:3](/[C:20]1[S:24][CH:23]=[C:22]([CH2:25][O:26][C:27]2[CH:28]=[C:29]([C:37]([O:39][CH3:40])=[O:38])[C:30](=[CH:35][CH:36]=2)[C:31]([O:33][CH3:34])=[O:32])[CH:21]=1)=[CH:4]\[CH2:5][CH2:6][C:7]([CH2:8][CH3:9])([OH:10])[CH2:18][CH3:19])[CH3:2]

Komponenten

4

Edukt 2

HCID 2724141Tetrabutylammonium FluorideHCID 69929440dimethyl 4-[5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)-3-thienylmethoxy]phthalate

Produkt 1

HCID 69928788HCID 69928788, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

1.7 g (2.9 mmol) of dimethyl 4-[5-((E)-1,5-diethyl-5-triethylsilanyloxyhept-1-enyl)-3-thienylmethoxy]phthalate are dissolved in 50 mL of anhydrous THF. 3.5 mL (3.5 mmol) of tetrabutylammonium fluoride (1.0 M in THF) are added and the medium is stirred at 60° C. for 3 hours. After the usual treatment and purification on silica gel (eluent: 70 heptane/30 ethyl acetate), the desired product is obtained in the form of a yellow oil (m=710 mg; Y=51%).

Aufarbeitung

  1. customAfter the usual treatment and purification on silica gel (eluent: 70 heptane/30 ethyl acetate)

Quellen und Nachweise

ORD-Eintrag
ord-aae79ad28af4436f8302b64513334676
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06706725B1

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