Diethyl Ether → 2,6-Dichloro-4-cyanobenzenediazonium tetrafluoroborate

HRID 494371

Reaktionsgleichung

Reaktionsgleichung von HRID 494371
[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[Cl:11].[F:12][B-:13]([F:16])([F:15])[F:14].[H+].[N:18](OCCC(C)C)=O.C(OCC)C>C(#N)C>[F:12][B-:13]([F:16])([F:15])[F:14].[Cl:11][C:3]1[CH:4]=[C:5]([C:6]#[N:7])[CH:8]=[C:9]([Cl:10])[C:2]=1[N+:1]#[N:18]

Komponenten

6

Edukt 4

HCID 3283Diethyl EtherHCID 8053Isoamyl NitriteHCID 28118Tetrafluoroboric acidHCID 5227064-Amino-3,5-dichlorobenzonitrile

Produkt 1

HCID 866096552,6-Dichloro-4-cyanobenzenediazonium tetrafluoroborateAusbeute 62,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

To a solution of 4-amino-3,5-dichlorobenzonitrile (2.00 g, 10.63 mmol) in acetonitrile (12 ml) was added dropwise tetrafluoroboric acid (2.80 ml, 21.27 mmol). After stirring for 10 min, isoamyl nitrite (1.50 ml, 10.63 mmol) was added and the reaction mixture was cooled to 0° C. After a further 10 min, diethyl ether (50 ml) was added and the resulting precipitate was collected by filtration and dried to give the titled compound (1.9 g).

Aufarbeitung

  1. waitAfter a further 10 min
  2. filtrationthe resulting precipitate was collected by filtration
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-642f2c82542c4638be26f180b45fce07
Quelldatensatz
uspto-grants-2009_05
Patentnummer
US07538134B2

Verknüpfte Notizen

Wird geladen…