2-(Benzyloxy)-6-butylpyridine → 6-Butylpyridin-2-ol

HRID 495247

Reaktionsgleichung

Reaktionsgleichung von HRID 495247
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][CH2:16][CH2:17][CH3:18])[N:10]=1)C1C=CC=CC=1.[H][H]>[Pd].C(O)C>[CH2:15]([C:11]1[N:10]=[C:9]([OH:8])[CH:14]=[CH:13][CH:12]=1)[CH2:16][CH2:17][CH3:18]

Komponenten

5

Edukt 2

HCID 666264812-(Benzyloxy)-6-butylpyridineHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 233521006-Butylpyridin-2-ol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a pressure reaction bottle were added 1.6 g 2-(benzyloxy)-6-butylpyridine, 0.2 g 5% palladium on carbon and 50 ml ethanol. The mixture was hydrogenated at 22 C and 40 psi hydrogen for 16 hours. Following filtration through celite and solvent removal, an oil was obtained that crystallized on standing to give 0.9 g.

Aufarbeitung

  1. customTo a pressure reaction bottle
  2. filtrationfiltration through celite and
  3. customsolvent removal
  4. customan oil was obtained
  5. customthat crystallized
  6. customto give 0.9 g

Quellen und Nachweise

ORD-Eintrag
ord-9846a64eb1374f1db7869785d1743f74
Quelldatensatz
uspto-grants-2009_05
Patentnummer
US07538931B2

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