(2-Dimethylamino-2'-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert-butyl ester → HCID 69489440, Verbindung

HRID 498197Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 498197
[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[C:13]([N+:14]([O-])=O)=[CH:12][C:11]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[F:23])=[C:10]([N:24]([CH3:26])[CH3:25])[CH:9]=1)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[C:13]([NH2:14])=[CH:12][C:11]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[F:23])=[C:10]([N:24]([CH3:25])[CH3:26])[CH:9]=1)([CH3:4])([CH3:3])[CH3:2]

Komponenten

3

Edukt 1

HCID 69489429(2-Dimethylamino-2'-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert-butyl ester

Produkt 1

HCID 69489440HCID 69489440, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

The title compound was prepared from (2-dimethylamino-2′-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert-butyl ester (Example C2) (4.54 g, 12.1 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light brown solid (3.324 g).

Quellen und Nachweise

ORD-Eintrag
ord-c2f230c7304242dd99da8965080f06de
Quelldatensatz
uspto-grants-2005_09
Patentnummer
US06949542B2

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