Potassium Carbonate → 4-(2-Aminopyrimidin-5-yl)-2,3-difluorobenzoic acid
Reaktionsgleichung
OB(O)[C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([F:12])[C:4]=1[F:13].Br[C:16]1[CH:17]=[N:18][C:19]([NH2:22])=[N:20][CH:21]=1.C(=O)([O-])[O-].[K+].[K+]>C1(C)C=CC=CC=1.C(O)C.O.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[NH2:22][C:19]1[N:20]=[CH:21][C:16]([C:3]2[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([F:12])[C:4]=2[F:13])=[CH:17][N:18]=1Komponenten
8
