HCID 178498471, Verbindung → Methyl 5-amino-1H-pyrazole-3-carboxylate

HRID 503807Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 503807
[N+:1]([C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1

Komponenten

4

Edukt 1

HCID 178498471HCID 178498471, Verbindung

Produkt 1

HCID 18445864Methyl 5-amino-1H-pyrazole-3-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To 14.0 g methyl 3-nitro-1H-pyrazole-5-carboxylate in 200 ml methanol are added 1.2 g Pd/C (10% w/w). The mixture is stirred under H2-atmosphere at room temperature for 18 h. The mixture is filtrated over kieselgur. The filtrate is concentrated and the crude product is used without further purification.

Aufarbeitung

  1. filtrationThe mixture is filtrated over kieselgur
  2. concentrationThe filtrate is concentrated
  3. customthe crude product is used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-14c9a9a466c94fd7a85eadc43ac130ca
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07776864B2

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