HCID 178420353, Verbindung → HCID 178511580, Verbindung
Reaktionsgleichung
C([N:8](CC1C=CC=CC=1)[C@H:9]1[CH2:14][CH2:13][C@H:12]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[O:18]1[CH2:17][CH2:16][N:15]([C@H:12]2[CH2:11][CH2:10][C@H:9]([NH2:8])[CH2:14][CH2:13]2)[CH2:20][CH2:19]1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
7.2 g (16.4 mmol) of trans-dibenzyl-4-morpholino-cyclohexylamine were dissolved in 100 mL of MeOH and hydrogenated on 1.4 g of Pd/C (10%) at 30-50° C. The solvent was eliminated in vacuo and the residue was crystallised from ethanol and conc. HCl. Yield: 3.9 g (93%); m.p. 312° C.
Aufarbeitung
- customthe residue was crystallised from ethanol and conc. HCl
Quellen und Nachweise
- ORD-Eintrag
- ord-1fe0c032f501493a9514e0edbfcf077d
- Quelldatensatz
- uspto-grants-2010_08
- Patentnummer
- US07786299B2
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