3-Methoxy-2-nitropyridine → 2-Amino-3-methoxypyridine
Reaktionsgleichung
[CH3:1][O:2][C:3]1[C:4]([N+:9]([O-])=O)=[N:5][CH:6]=[CH:7][CH:8]=1>CO.[Pd]>[CH3:1][O:2][C:3]1[C:4]([NH2:9])=[N:5][CH:6]=[CH:7][CH:8]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
3-Methoxy-2-nitro-pyridine (53, 7.00 g, 45.4 mmol) in 100 mL of methanol, was degassed and palladium (0.7 g, 20%) was added. The reaction was stirred at room temperature for one day under a hydrogen balloon. The reaction was filtered through celite and the filtrate concentrated under vacuum to provide the desired compound (54, 5.555 g). MS (ESI) [M+H+]+=125.3.
Aufarbeitung
- filtrationThe reaction was filtered through celite
- concentrationthe filtrate concentrated under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-9318cbde3ac744f2823c3446eebe84ba
- Quelldatensatz
- uspto-grants-2015_08
- Patentnummer
- US09096593B2
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