N,N-Dibutylaniline → 5-Butoxy-4-methyl-1,3-oxazole

HRID 51210

Reaktionsgleichung

Reaktionsgleichung von HRID 51210
[N+:1]([CH:3]([CH3:11])[C:4]([O:6][CH2:7][CH2:8][CH2:9][CH3:10])=[O:5])#[C-:2].C(N(CCCC)C1C=CC=CC=1)CCC>>[CH3:11][C:3]1[N:1]=[CH:2][O:5][C:4]=1[O:6][CH2:7][CH2:8][CH2:9][CH3:10]

Komponenten

3

Edukt 2

HCID 61154N,N-DibutylanilineHCID 11171108n-Butyl alpha-isocyanopropionate

Produkt 1

HCID 98774405-Butoxy-4-methyl-1,3-oxazoleAusbeute 98,7 %

Versuchsvorschrift

Example 5 is repeated except that a mixture of 11.8% by weight of n-butyl α-isocyanopropionate and 88.2% by weight of N,N-dibutylaniline is added continuously via the inlet (A). 4-Methyl-5-n-butoxyoxazole is obtained in a yield of 98.7% via the top takeoff B and the amine via the sidestream takeoff D.

Quellen und Nachweise

ORD-Eintrag
ord-2e9a3f31681747fb86ec406eef7c2bbf
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06713630B2

Verknüpfte Notizen

Wird geladen…