Methyl 4-bromobenzoate → 4-Bromobenzohydrazide

HRID 516477

Reaktionsgleichung

Reaktionsgleichung von HRID 516477
C[O:2][C:3](=O)[C:4]1[CH:9]=[CH:8][C:7]([Br:10])=[CH:6][CH:5]=1.O.[NH2:13][NH2:14]>C(O)C>[Br:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([NH:13][NH2:14])=[O:2])=[CH:5][CH:6]=1

Komponenten

4

Edukt 2

HCID 12081Methyl 4-bromobenzoateHCID 24654Hydrazine hydrate (1:1)

Produkt 1

HCID 222194-BromobenzohydrazideAusbeute 67 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added thereto, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added thereto, and the mixture was heated and stirred at 78° C. for 5 hours. The obtained solid was washed with water and collected by suction filtration; thus, 2.0 g of a white solid of 4-bromobenzohydrazide that was an object was obtained in the yield of 67%.

Aufarbeitung

  1. temperaturethe mixture was heated
  2. stirringstirred at 78° C. for 5 hours
  3. washThe obtained solid was washed with water
  4. filtrationcollected by suction filtration
  5. customwas obtained in the yield of 67%

Quellen und Nachweise

ORD-Eintrag
ord-b7a9aeaee135487680a28efcce79c560
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09112170B2

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