Sodium Bromide → 3-Bromo-1-(3-bromophenyl)butan-2-one

HRID 517551Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 517551
[Na+].[Br-:2].[Br:3][C:4]1[CH:5]=[C:6]([CH2:10][C:11](=[O:15])[CH:12](Cl)[CH3:13])[CH:7]=[CH:8][CH:9]=1>CC(C)=O.CCCCCC>[Br:2][CH:12]([CH3:13])[C:11](=[O:15])[CH2:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([Br:3])[CH:5]=1

Komponenten

5

Edukt 2

HCID 253881Sodium BromideHCID 867114911-(3-Bromophenyl)-3-chlorobutan-2-one

Produkt 1

HCID 867114923-Bromo-1-(3-bromophenyl)butan-2-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 8058HexaneLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

A mixture of NaBr (197 mg, 1.9 mmol) and 1-(3-bromophenyl)-3-chlorobutan-2-one (100 mg, 0.38 mmol) in acetone (2 ml) was stirred at 70° C. for 3 h. The mixture was diluted with hexane and filtered to remove the solid. The solvent was removed under reduced pressure and the residue was used for the next step without further purification. MS (ES+) C10H10Br2O requires: 303, 305 found: 304, 306 [M+H]+(1:1).

Aufarbeitung

  1. filtrationfiltered
  2. customto remove the solid
  3. customThe solvent was removed under reduced pressure
  4. customthe residue was used for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-8d51c3e1bfe7421f991cd64aee8c6583
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09115120B2

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