Reaktionsgleichung
[CH2:1]([NH:3][C:4]1[C:12]2[S:11][C:10]([NH2:13])=[N:9][C:8]=2[C:7]([O:14][CH3:15])=[CH:6][CH:5]=1)[CH3:2].[C:16](Cl)(=[O:18])[CH3:17].Cl.[CH3:21][C:22]1[CH:23]=[C:24]([CH:28]=[CH:29][N:30]=1)[C:25](O)=[O:26].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CN1CCOCC1>ClCCl.C1COCC1.N1C=CC=CC=1>[C:16]([N:3]([CH2:1][CH3:2])[C:4]1[C:12]2[S:11][C:10]([NH:13][C:25](=[O:26])[C:24]3[CH:28]=[CH:29][N:30]=[C:22]([CH3:21])[CH:23]=3)=[N:9][C:8]=2[C:7]([O:14][CH3:15])=[CH:6][CH:5]=1)(=[O:18])[CH3:17]Komponenten
9
Edukt 5
HCID 6367Acetyl chloride
HCID 79724-Methylmorpholine
HCID 27628242-methylpyridine-4-carboxylic Acid Hydrochloride
HCID 9886157Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)
HCID 22737006N7-ethyl-4-methoxy-benzothiazole-2,7-diamineProdukt 1
Reagenzien, Katalysatoren, Lösungsmittel 3
Versuchsvorschrift
From N7-ethyl-4-methoxy-benzothiazole-2,7-diamine with pyridine and acetyl chloride in dichloromethane and THF, then treatment with 2-methyl-isonicotinic acid hydrochloride, HATU and N-methylmopholine in THF. ES-MS m/e (%): 385 (M+H+, 100).
Quellen und Nachweise
- ORD-Eintrag
- ord-5fc07a839a3c48e098d0eb0d588d6cf7
- Quelldatensatz
- uspto-grants-2004_03
- Patentnummer
- US06713499B2
Verknüpfte Notizen
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